Endocrine Abstracts

Context: Thiazolidiones (TZD) improves insulin sensitivity in type 2 diabetes via effects on fat metabolism, whereas growth hormone (GH) stimulates lipolysis and induces insulin resistance.Objective: To evaluate the effects of TZD on fat metabolism and insulin sensitivity in GH-treated GH deficient (GHD) patients.Design: Randomized, placebo-controlled, double-blind parallel-group study including 20 GHD patients on continued GH repl...